Pathway Editing
Please click on the pathway editing references below to read the entire article. Check back occasionally as new pathway editing articles will be posted.2008
- Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications
( ISBN: 978-0-470-10705-8 )
- Targeting Telomerase: Therapeutic Options for Cancer Treatment
( Springer-Verlag. P247 – 284, 2008. ISBN: 978-3-540-73708-7 )
2007
- Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells
( Drug Discovery Today, Volume 12, Numbers 15/16, August 2007 )
- Telomerase redefined: Integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity
( Biochimie (2007), doi:10.1016/j.biochi.2007.07.025 )
Mary E. Edgerton, a pathologist performing cancer research at MD Anderson and a long-term client, says “I have been using Metacore for many years in my research into pathways and networks that control aggressive behavior in cancers. I am currently using it to infer networks from analysis of gene expression array data for pathways in lung, brain, and breast cancer. I also use the curated pathways to formulate mathematical models of molecular networks that predict tumor behavior using multiscale modeling. Not only do I find the product to be very useful, but I also appreciate the responsiveness of the staff at Genego to my technical questions and suggestions.”