Gene Expression

Please click on the gene expression references below to read the entire article. Check back occasionally as new gene expression articles will be posted.

2007

• Nutrigenomics: concepts and applications to pharmacogenomics and clinical medicine
  ( Pharmacogenomics. 8(4) 2007 )
• Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.
  ( Toxicol. Appl. Pharmacol. (2007), doi:10.1016/j.taap.2007.08.026 )
• Toxicogenomics in the assessment of immunotoxicity
  ( Methods 41, 132-141, 2007 )
• Chemoinformatics: Theory, Practice, & Products
  ( Springer, 2007 )
• Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling
  ( Immunogenetics, accepted )
• In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics
  ( Toxicology 2007, accepted )
• Host transcription profiles upon primary Respiratory Syncytial Virus infection
  ( Journal of Virology, June 2007, p. 5958-5967 )
• Quantitative proteomic analysis reveals that proteins differentially expressed in chronic pancreatitis are also frequently involved in pancreatic cancer
  ( Mol Cell Proteomics 12 May 2007 )
• Huntington's disease: from experimental results to interaction networks, patho-pathway construction and disease hypothesis
  ( BMC Systems Biology 2007, 1(Suppl 1):P45 )
• Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling
  ( Cancer Res 2007; 67: (7). April 1, 2007 )
• Gene expression response of the rat small intestine following oral Salmonella infection
  ( Physiol Genomics. 2007 Mar 27 )
• Molecular Definition of Breast Tumor Heterogeneity
  ( Cancer Cell 11, 259-273, March 2007 )
• High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations
  ( BMC Genomics 2007, 8:28 doi:10.1186/1471-2164-8-28 )

2006

• Gene Expression Profiling of Bis(tri-n-butyltin)oxide (TBTO)-Induced Immunotoxicity in Mice and Rats
  ( Journal of Immunotoxicology, 3:227-244, 2006 )
• Chronic quercetin exposure affects fatty acid catabolism in rat lung
  ( Cell. Mol. Life Sci. 63 (2006) 2847 - 2858. December 2006 )
• Mass Spectrometry-based Proteomic Studies of Human Anaplastic Large Cell Lymphoma
  ( Molecular & Cellular Proteomics 5:1787-1798, 2006 )
• Different Signaling Pathways in the Livers of Patients With Chronic Hepatitis B or Chronic Hepatitis C
  ( HEPATOLOGY, November 2006 )
• Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
  ( Physiol Genomics. October 31, 2006 )
• Collaboration with GeneGo provides seamless access to compound databases, patents, literature and biological pathways
  ( Molecular Connection Vol 24 No 4 2006 )
• Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses
  ( Oncogenomics (2006), 1-12 )
• Defective Ribosomal Protein Gene Expression Alters Transcription, Translation, Apoptosis, and Oncogenic Pathways in Diamond-Blackfan Anemia
  ( Stem Cell, 2006, 24, (9)2034-2044 )
• Evaluation of immunomodulation by Lactobacillus casei Shirota: immune function, autoimmunity and gene expression
  ( International Journal of Food Microbiology 112, 8-18, 2006 )
• Nicotinic modulation of gene expression in SH-SY5Y neuroblastoma cells
  ( Brain Research 1116 (2006) 39-49 )
• Gene Expression profiling of Waldenström&s Macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma
  ( Blood First Edition Paper, prepublished online June 27, 2006; DOI 10.1182/blood-2006-02-005488 )
• High-protein and high-carbohydrate breakfasts differentially change the transcriptome of human blood cells
  ( Am J Clin Nutr 2006;84:1233-41 )
• Identification of interactive gene networks: A novel approach in gene array profiling of myometrial events during guinea pig pregnancy
  ( American Journal of Obstetrics and Gynecology (2006) 194, 1513-23 )
• Microarray Platform Comparisons - Commentary on Barnes et al. (2005)
  ( Affymetrix White Paper, April 19, 2006 )
• Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes
  ( Genomics, 2006 )
• Cognitive dysfunction in NF1 knock-out mice may result from altered vesicular trafficking of APP/DRD3 complex
  ( BMC Neuroscience 2006, 7:22 )
• Biological Pathways at Your Fingertips
  ( iPath™ Quest Magazine, Vol.3, No.1, 77-81, 2006 )
• Comprehensive Network Analysis of Glaucoma Pathophisiology
  ( Mol. Sys. Biol. )

2005

• Network analysis of human OMICs data: the toolkit and statistical evaluation
  ( Proc. Nattl. Acad. Sci. USA )
• Redox proteomic analysis of altered neuronal signaling in a PS1+APP mouse model of Alzheimer's disease
  ( J. Alzheimer Disease, in press )
• Systems level analysis of drug metabolism and its effects in human biology
  ( Bioinformatics. 2005, submitted )
• A Toolkit and Statistical Evaluation Method for Network Analysis of Human High Throughput Data
  ( FEBS Lett 2005, submitted )
• Reengineering the pharmaceutical industry by crash-testing molecules
  ( Drug Disc Today, Vol.10 Num. 17, September 2005 )
• Use of the local lymph node assay in assessment of immune function
  ( Toxicology 211, 107-114, 2005 )
• Systems Biology; Applications in drug discovery
  ( In: Drug Discovery Handbook, Wiley, 2005 )
• Systems Level Network Analysis of OMICs Data
  ( Gen. Eng. News, 2005, 25, 1, 28-29 )
• Biological networks and analysis of experimental data in drug discovery
  ( Drug Discovery Today, DDT, Volume 10, Number 9, May 2005 )
• A Novel Method for Generation of Signature Networks as Biomarkers from Complex High Throughput Data
  ( Tox. Letters 158: 20-29, 2005 )
• Application of systems biology to absorption, distribution, metabolism, excretion and toxicity
  ( Trends in Pharmacological Sciences, Vol.26, No.4, 202-209, April 2005 )

2004

• Translation research: from accurate diagnosis to appropriate treatment
  ( Journal of Translational Medicine 2004, 2:35 )
• Kohonen Maps for Prediction of Binding to Human Cytochrome P450 3A4
  ( Drug Metabolism and Disposition, DMD 32:1183-1189, 2004 )
• Early Prediction of Drug Metabolism and Toxicity: Systems Biology Approach and Modeling
  ( Drug Discovery Today, DDT Vol.9, No.3, February 2004 )

2003

• Modeling of Human Cytochrome P450-Mediated Drug Metabolism Using Unsupervised Machine Learning Approach
  ( Journal of Medicinal Chemistry, 46: 3631-3643, 2003 )