Partners and Collaborations

GeneGo has integrated Accelrys Accord technology into MetaDrug™. For
more information: http://www.genego.com/pressReleases.php#2005-06-06

GeneGo is an Affymetrix software solution partner. MetaCore™ and MetaDrug™
recognize Afftmetrix ID’s and have a parser for uploading Affymetrix
chip data. MetaCore™ and MetaDrug™ are gene chip compatible.
http://www.genego.com/pressReleases.php#2005-09-19

GeneGo and researchers from the National Center for Toxicological Research,
FDA have integrated Array Tracker with Metacore™.
http://www.genego.com/pressReleases.php#2005-10-10

Agilent’s bio-analytical measurement business (Life Science & Chemical Analysis, LSCA) provides
application-focused solutions that include instruments, software, consumables and services that enable
customers to identify, quantify and analyze the physical and biological properties of substances and
products. Our bio-analytical measurement business employed approximately 4,000 people worldwide as of
October 31, 2005. For more information visit the LSCA website at
www.agilent.com.
Markets: The markets for our bio-analytical measurement business include life
sciences, including the pharmaceutical analysis, gene expression and proteomics markets, and chemical
analysis, including the petrochemical, environmental, homeland security and forensics and
bioagriculture and food safety markets.
Product areas: The seven key product categories for the bio-analytical measurements business
include: microarrays, microfluidics, gas chromatography, liquid chromatography, mass spectrometry,
software and informatics, and related consumables, reagents and services.
http://www.genego.com/pressReleases.php#2006-06-06

BIOCRATES is the leader in targeted metabolomics. They pioneered an integrated mass spectrometry based
technology platform for extracting detailed information residing in metabolic networks. Their unique,
quantitative approach incorporates numerous internal standards and enables them to immediately identify
metabolites, measure their absolute concentrations, and map them to their respective pathways. In
addition, they are the only company offering a convenient, disposable kit covering several metabolite
classes simultaneously.
Customers can take metabolomic data generated from BIOCRATES’ kit product and feed it into GeneGo’s
MetaCore™ product, allowing for a more complete understanding of biochemical pathways using a
comprehensive systems biology approach.

CambridgeSoft develops and markets life science enterprise solutions for pharmaceutical, biotechnology,
chemical companies and academic research organizations. Software products include enterprise, workgroup
and desktop, versions of Chem & Bio Office, including Chem & Bio Draw, with knowledge
management, chemical and biological informatics, and scientific database solutions.
Web sites include ChemFinder.Com and
ChemBioNews.Com for indexed database content and news, and
SciStore.Com for e-commerce.
For information about CambridgeSoft products, services, and resellers worldwide, please visit
www.cambridgesoft.com, or call 800 315-7300 or 617 588-9100

Chenomx, Inc. is a privately-held Canadian company that specializes in the development of complex mixture
analysis software for broad application in life science technologies. With world-class expertise in NMR
spectroscopy, pharmaceutical sciences, and computer software, Chenomx offers a broad range of software products
and compound databases to support the metabolomics communities' research efforts. Chenomx's flagship product,
Chenomx NMR Suite, provides a rich set of tools for identifying and quantifying metabolites in complex NMR
Spectra.

Expression Analysis is the industry’s leading provider of genomic services including Affymetrix
GeneChip® brand microarray technology, Illumina BeadChip® technology and TaqMan® PCR
technology services for clinical trials. Specializing in gene expression, genotyping and resequencing,
our GLP and CLIA registered laboratory provides start to finish contract testing offering high
throughput, high quality and cost-effective results in a regulatory compliant environment to advance
genomic science.

Genedata provides software solutions and professional services designed to increase productivity in
drug discovery, biomarker identification, biomarker prediction and systems biology research.
Genedata Expressionist® is unique in its ability to capture, integrate and analyze data from
high-throughput transcriptomics, proteomics and metabolomics research. Genedata Expressionist®
and GeneGo Metacore™ have been integrated and implemented in partnership with several
pharmaceutical companies to provide a proven system for highly productive biomarker and systems
biology research.
To learn more about Expressionist® please visit www.genedata.com
http://www.genego.com/pressReleases.php#2006-02-13

GeneGo has integrated Golden Helix ChemTree into MetaDrug™.

GVK Biosciences is one of India’s premier Contract Research Organizations, providing an integrated platform of
research services across the Pharma R&D value chain to a growing number of global Pharma and Biotech companies.
The company combines science, innovation and resources to help clients address their Drug Discovery and Development
challenges. Currently the company has more than 1,300 employees spread across facilities in Hyderabad, Chennai and
Gurgaon.

The illumina-Connect program is a software/hardware network connecting Illumina with researchers in genomics, genetics, and sequencing communities.
This connection offers customers unparalleled access to world-class bioinformatics software for handling data generated from genomic, genetic, and
sequencing experiments. Our partners in this program integrate Illumina data with their application platforms by designing plug-ins that hook into
the BeadStudio platform.
At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, enabling studies that were not even imaginable a few years ago. These studies will help make personalized medicine possible.

InforSense Limited, the leader in integrative analytics, enables organizations to orchestrate and
optimize their business-critical decision-making processes. Leading pharmaceutical and biotechnology,
consumer goods, financial services companies, and research institutes are using the company’s flagship
product, InforSense KDE, to enhance productivity across life science R&D, healthcare, and business
analytics. The company is privately held, with European headquarters in London, UK and North American
headquarters in Cambridge, Massachusetts. For more information visit
www.inforsense.com.
The integration of InforSense’s integrated, interactive workflow-based data mining technology and
GeneGo’s unique reference system for curated pathway analysis allows researchers to query their data
and share their results across the research and development value chain. In addition to the integration
of InforSense KDE and MetaCore™, which is already available, the companies are in the process of
integrating InforSense KDE with both MetaBase™ and MetaDrug™.
http://www.genego.com/pressReleases.php#2006-04-11

Invitrogen Corp. (www.invitrogen.com) and GeneGo
(www.genego.com) have partnered to develop the iPath™
Online BioAtlas (www.invitrogen.com/iPath) a FREE comprehensive online resource for gene- and
protein-based scientific research. The iPath™ tool offers scientists worldwide a user-friendly
interface and highly educational bioinformatics content for exploring biological pathways,
investigating gene/protein function, and selecting appropriate Invitrogen™ products for specific
research applications.
iPath™ content currently includes 225 human cell signaling and metabolic pathways covering
over 2,700 distinct genes/proteins, over 12,000 gene- and protein-related Invitrogen™ products,
as well as extensive resources of public data. The human biological pathway maps are provided by
GeneGo, the leader in pathway analysis tools and content. GeneGo scientists have spent years combing
peer-reviewed scientific articles to put together the most comprehensive, high-quality maps currently
available. The resulting data is presented in an easy-to-use web interface, with additional information
just few clicks away.
http://www.genego.com/pressReleases.php#2004-06-01

Elsevier MDL provides informatics, database and workflow solutions that accelerate successful R&D by improving
the speed and quality of scientists' decision making. For more information, visit
www.mdl.com.
DiscoveryGate® (www.discoverygate.com) is your first
stop for scientific information and answers to discovery questions. A powerful Web-based discovery environment,
DiscoveryGate integrates, indexes, and links scientific information to give you immediate access to compounds and
related data, reactions, original journal articles and patents, and authoritative reference works on synthetic
methodologies-all from a single entry point.
How the integration of the GeneGo databases (MetaCore™ and MetaDrug™) on the DiscoveryGate content
platform works:
http://www.genego.com/PubFTP/GeneGoreprnt.pdf
http://www.genego.com/pressReleases.php#2006-07-20

Monarch LifeSciences provides services in protein biomarker discovery, development and validation for the
pharmaceutical and biotech industries. Monarch’s biomarker discovery services include experimental design,
proprietary sample preparation methods and quantification algorithms to ensure the generation of quality data. The
LifeMarker™ Assay supports both pre-clinical and clinical applications of biomarkers and provides accurate high
throughput analysis of proteins without the need for an antibody. For more information, please visit the
company’s web site www.monarchlifesciences.com

Both MetaCore™ and MetaDrug™ use Oracle database technology.

QFAB is a specialist provider of bioinformatics solutions that underpin the life science discovery process. QFAB uses a Systems Biology approach and
applies leading-edge information and communications technology, such as GeneGo, to leverage the technical advances and foster innovation in
biotechnology, health, and environmental research.
Built around its professional technical team, QFAB supports the bioinformatics requirements of research-intensive universities, institutions and
industry including secure access to very large databases, specialist integrated software, high-performance computing, terabyte storage, data
integration technologies and expert services.

Rosetta Biosoftware develops informatics solutions and provides services that enable research
organizations to efficiently and effectively conduct life-saving discoveries and develop drugs.
Our mission is to be the premier provider of scalable software solutions to empower research that
improves the quality of human life. We provide value to discovery and development efforts by offering
customizable informatics solutions and services that are adaptable to your needs. We are a
customer-driven organization with the scientific expertise to effectively complement your internal
informatics groups or serve as an informatics resource.
http://www.genego.com/pressReleases.php#2005-07-18

SciTegic develops and markets informatics software to the pharmaceutical and biotechnology industries.
SciTegic has pioneered a technology approach called “Data Pipelining” to process drug discovery data
with unprecedented flexibility. Pipeline Pilot is a high-throughput data analysis and mining system of
drug discovery informatics. With this package, a user may define and perform a complex series of
operations on extremely large data sets in real time. Pipeline Pilot serves as the ideal platform for
processing the growing volume of data being generated in modern automated laboratories
http://www.genego.com/pressReleases.php#2006-01-09

Sierra Analytics provides software applications and tools for processing and analysis
of mass spectral data. Sierra’s Apex™ software works in synchrony with
GeneGo’s metabolite prediction tools to confirm the presence of predicted
metabolites in LC/MS and LC/MS/MS datasets using sophisticated algorithms
for chemical structure and spectrum correlation.
Visit Sierra’s Web site at
http://www.MassSpec.com to learn more about Apex.

Spotfire, the Information Insight CompanySM, is a leading provider of enterprise analytics software that helps professionals quickly discover new and actionable insights in information. For thousands of business professionals faced with day-to-day decisions, Spotfire offers a visual and interactive analytics experience that helps them make decisions with speed and confidence. Distinguished by its ease of use and analytic power, Spotfire software rapidly reveals unseen threats and illuminates new opportunities, creating significant economic value. Spotfire’s customers include industry leaders among the Global 2000 that have deployed Spotfire analytics to gain an information advantage over their competitors. For more information, visit
http://www.spotfire.com.

XB TransMed Solutions provides fully integrated bio-analytical systems and services
supporting the entire biological scientific work process from discovery through clinical application.
XB BioIntegration Suite, an integrated software solution designed by translational researchers for
translational research, allows management and analysis of disparate data sets including molecular,
cellular, pre-clinical and clinical data. Applications for XB BIS include target identification,
biomarker discovery, diagnostic development, clinical trial support, discovery of new indications and
tailored treatment strategies.
XB TransMed Solutions is a privately held company based in Grand Rapids MI. For more information visit
www.xbtransmed.com
http://www.genego.com/pressReleases.php#2006-04-24